发明名称 |
Methods for measuring platelet reactivity of patients that have received drug eluting stents |
摘要 |
A method is providing for measuring platelet reactivity of a PCI patient that has a (DES). A blood sample is obtained from the patient. The blood sample is mixed in combination with 1) an anticoagulant; 2) sufficient buffer to maintain the pH and salt concentration of the anticoagulated blood within a range suitable for platelet aggregation; 3) a platelet GPIIb/IIIa receptor ligand immobilized on a solid surface; 4) one or more agents to enhance a signal transduction pathway and 5) a receptor activator. The combination is incubated under conditions for agglutinating particles. Platelet-mediated agglutination is assessed in the mixture. The absence of agglutination indicates that the patient has reduced ability to form platelet thrombi.
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申请公布号 |
US2007243632(A1) |
申请公布日期 |
2007.10.18 |
申请号 |
US20070742684 |
申请日期 |
2007.05.01 |
申请人 |
COLLER BARRY S;DURBIN DENNIS |
发明人 |
COLLER BARRY S.;DURBIN DENNIS |
分类号 |
G01N33/50;A61K31/557;A61K39/395;G01N33/567 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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