摘要 |
The use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein X<SUP>1</SUP>, X<SUP>2</SUP>, X<SUP>3</SUP>, X<SUP>4</SUP>, R<SUP>a</SUP>, p, R<SUP>1</SUP>, Z, Y, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>are as defined in the specification, in the preparation of a medicament for the treatment of C-C chemokine mediated conditions, such as inflammatory disease. Certain compounds of formula (I) are novel and these, together with their preparation are also described and claimed.
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