| 发明名称 |
CINNOLINE AND QUINAZOLINE DERIVATES AS PHOSPHODIESTERASE 10 INHIBITORS |
| 摘要 |
The present invention is directed to cinnoline and quinazoline compounds of formula (I) that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.
|
| 申请公布号 |
WO2007100880(A8) |
申请公布日期 |
2007.10.18 |
| 申请号 |
WO2007US05233 |
申请日期 |
2007.02.27 |
| 申请人 |
AMGEN INC.;MEMORY PHARMACEUTICALS CORPORATION;HITCHCOCK, STEPHEN, A.;ARRINGTON, MARK, P. |
发明人 |
HITCHCOCK, STEPHEN, A.;ARRINGTON, MARK, P. |
| 分类号 |
C07D237/28;A61K31/495;A61K31/535;A61P3/10;A61P25/00;C07D401/04;C07D401/12;C07D403/04;C07D403/10;C07D405/04;C07D413/04;C07D413/10;C07D417/04;C07D471/04 |
主分类号 |
C07D237/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
