POLYPEPTIDES WITH ENHANCED ANTI-INFLAMMATORY AND DECREASED CYTOTOXIC PROPERTIES AND RELATING METHODS
摘要
The invention provides a polypeptide containing at least one IgG Fc region region, said polypeptide having a higher anti- inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide.
申请公布号
WO2007117505(A2)
申请公布日期
2007.10.18
申请号
WO2007US08396
申请日期
2007.04.03
申请人
THE ROCKEFELLER UNIVERSITY;RAVETCH, JEFFREY, V.;YOSHIKATUS, KANEKO;FALK, NIMMERJAHN