<p>The present invention relates to a new process for preparing the oxazolidinone antibacterial agent linezolid which comprises the reaction of an (S)-I -chloro-3- (benzyIidenylamino)-propan-2-ol with a morpholinyl fluorophenyl carbamate to afford a protected imine intermediate which, upon hydrolysis and acylation, yields linezolid in high yield.</p>
申请公布号
WO2007116284(A1)
申请公布日期
2007.10.18
申请号
WO2007IB00882
申请日期
2007.03.26
申请人
PFIZER PRODUCTS INC.;IMBORDINO, RICK, JOSEPH;PERRAULT, WILLIAM, ROLAND;REEDER, MICHAEL, ROBERT
发明人
IMBORDINO, RICK, JOSEPH;PERRAULT, WILLIAM, ROLAND;REEDER, MICHAEL, ROBERT
