ORAL PHARMACEUTICAL COATED COMPOSITION FOR PULSATILE RELEASE

摘要

A pharmaceutical composition comprising a pharmaceutically active agent, a core, a coating comprising an inner film comprising cellulose acetate and hydroxypropylmethylcellulose in a ratio of cellulose acetate : hydroxypropylmethylcellulose of 80 % to 99.5 % : 0.5 % to 20 % and an outer film comprising ethylcellulose and hydroxypropylcellulose in a ratio of ethylcellulose : hydroxypropylcellulose of 50 % to 80 % : 20 % to 50 %.