PHAGE DISPLAY BY NOVEL FILAMENTOUS BACTERIOPHAGE

摘要

[PROBLEMS] To provide a phage display vector which can be fused in the inside of pIII and a phage display method using the vector. [MEANS FOR SOLVING PROBLEMS] Disclosed is a phage display method which is characterized by using a mutant pIII protein having an amino acid residue inserted between a proline residue at position 11 and a histidine residue at position 12 in an M13 phage pIII protein as depicted in SEQ ID NO:1. The method enables to produce a random peptide with high efficiency and to provide a novel source in peptide conformation.