| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide Corynebacterium glutamicum genes encoding proteins involved in homeostasis and adaptation, and to provide utilization thereof for adjusting the production of fine chemicals. <P>SOLUTION: Isolated nucleic acid molecules, designated HA nucleic acid molecules, which encode novel HA proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing HA nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated HA proteins, mutated HA proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of HA genes in this organism. <P>COPYRIGHT: (C)2008,JPO&INPIT |
