发明名称 COMPOSITION AND METHOD FOR TREATING CANCER AND HYPER PROLIFERATIVE DISORDERS
摘要 PROBLEM TO BE SOLVED: To provide a method for reducing or inhibiting a growth factor in cancer cells and in tissues. SOLUTION: An immunogenic growth factor-containing compositions are administered to a human or animal with a cancer or tumor. The immunogenic compositions elicit the production of antibodies specific for the growth factor which reduce the level of circulating growth factor, thus reducing or eliminating the proliferation of the cancer. The present invention encompasses growth factor-containing liposomes and vesicles having portions of growth factor externally presented on their surfaces. The present invention also includes antibodies specific for growth factor. Thus, growth factor levels are reduced either by active immunization of an individual using immunogenic growth factor-containing compositions or by passive immunization via administering to the individual an antibody or a group of antibodies specific for growth factor. COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2007262102(A) 申请公布日期 2007.10.11
申请号 JP20070191910 申请日期 2007.07.24
申请人 ENTREMED INC 发明人 NACY CAROL A;HOLADAY JOHN W
分类号 A61K39/00;A61K9/127;A61K38/00;A61K38/18;A61K38/22;A61K38/27;A61K39/385;A61K39/39;A61P35/00;C07K16/22 主分类号 A61K39/00
代理机构 代理人
主权项
地址