发明名称 AZABICYCLO [3. 1. O] HEXYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS
摘要 <p>The present invention relates to novel compounds or pharmaceutically acceptable saltsthereof: wherein G is selected from a group consisting of : phenyl, a 5- or 6-membered monocyclic heteroaryl group, or a 8- to 11-membered heteroaryl bicyclic group; A is a group P wherein P is p is an integer ranging from 0 to 5; Rl, R2, R3, R4,R5 and R7 are as defined in the claims, processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D3 receptors, e.g. to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, or premature ejaculation.</p>
申请公布号 WO2007113260(A1) 申请公布日期 2007.10.11
申请号 WO2007EP53117 申请日期 2007.03.30
申请人 GLAXO GROUP LIMITED;BERTANI, BARBARA;CHECCHIA, ANNA;DI FABIO, ROMANO;GENTILE, GABRIELLA;MICHELI, FABRIZIO;PASQUARELLO, ALESSANDRA;TERRENI, SILVIA 发明人 BERTANI, BARBARA;CHECCHIA, ANNA;DI FABIO, ROMANO;GENTILE, GABRIELLA;MICHELI, FABRIZIO;PASQUARELLO, ALESSANDRA;TERRENI, SILVIA
分类号 C07D401/14;A61K31/513;A61P25/00;C07D403/06;C07D405/14 主分类号 C07D401/14
代理机构 代理人
主权项
地址