METHOD FOR PRODUCTION OF N-(3-PHENYL-2-NORCAMPHANYL)-N-ETNYLAMINE HYDROCHLORIDE

摘要

FIELD: organic chemistry. ^ SUBSTANCE: claimed method includes reduction of 2-nitro-3-phenyl-Delta5-norcamphene with active hydrogen obtaining by reaction of aluminum containing in nickel-aluminum alloy with potassium hydroxide, wherein 1 N potassium hydroxide solution and powdered nickel-aluminum alloy are added to 2-nitro-3-phenyl-Delta5-norcamphene solution in tetrahydrofurane followed by treatment thereof with ethanol in presence of skeletal nickel catalyst forming in reduction step to produce N-3-phenyl-2-norcamphanyl)-N-etnylamine followed interaction thereof with hydrogen chloride and isolation of target product. Compound of present invention is useful in medicine as active ingredient of preparations with tonic action. ^ EFFECT: new method for production of N-(3-phenyl-2-norcamphanyl)-N-etnylamine hydrochloride. ^ 1 cl, 1 ex