| 发明名称 |
2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS |
| 摘要 |
This invention relates to 8-aza prostanoid analogs which are generally EP4 receptor agonists and are represented by Formula I:wherein Q, B, X, J, Z, A and R<1>-R<6 >are as defined, their synthesis and use for treatment of osteoporosis and increasing bone density.
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| 申请公布号 |
PT1408961(E) |
申请公布日期 |
2007.10.10 |
| 申请号 |
PT20020762347T |
申请日期 |
2002.07.11 |
| 申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
DAVID BERNARD SMITH;TODD RICHARD ELWORTHY;MICHAEL GARRET ROEPEL |
| 分类号 |
A61K31/4015;C07D207/20;A61P19/00;A61P19/10;C07D207/12;C07D207/26;C07D207/273;C07D207/46;C07D405/06 |
主分类号 |
A61K31/4015 |
| 代理机构 |
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代理人 |
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