| 发明名称 |
СПОСОБНЫЙ К ИНТЕРФЕРЕНЦИИ ДУПЛЕКС РНК, ИМЕЮЩИЙ ТУПЫЕ КОНЦЫ И 3, -МОДИФИКАЦИИ |
| 摘要 |
The present invention relates to double-stranded RNA compounds with at least one blunt end comprising at least one 3'-end modified to an hydroxypropylphosphodiester.
The RNA of the invention is useful as a medicament, for inhibiting expression of a target gene and for drug screening. |
| 申请公布号 |
RU2006109547(A) |
申请公布日期 |
2007.10.10 |
| 申请号 |
RU20060109547 |
申请日期 |
2004.08.27 |
| 申请人 |
НОВАРТИС АГ (CH) |
发明人 |
ВАЙЛЕР Ян (DE);ХОЛЛ Джонатан (CH);БОЛОНЬЯ Жан-Шарль (CH);НАТТ Франсуа Жан-Шарль (CH);ХЭНЕР Роберт (CH) |
| 分类号 |
C12N15/11;A61K48/00 |
主分类号 |
C12N15/11 |
| 代理机构 |
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