| 发明名称 |
PROCESS FOR THE MANUFACTURE OF A PRECURSOR OF VITAMIN B1 |
| 摘要 |
<p>The present invention relates to a novel process for the manufacture of Grewe-diamine comprising the following step: hydrolyzing a compound of formula (II), wherein R is hydrogen or straight- or branched chain C1-4 alkyl, with an aqueous alkali or alkaline-earth metal hydroxide solution, characterized in that the hydrolysis is carried out in the presence of an organic solvent.</p> |
| 申请公布号 |
EP1841745(A2) |
申请公布日期 |
2007.10.10 |
| 申请号 |
EP20060704494 |
申请日期 |
2006.01.24 |
| 申请人 |
DSM IP ASSETS B.V. |
发明人 |
BONRATH, WERNER;FISCHESSER, JOCELYN;GIRAUDI, LISA;KARGE, REINHARD |
| 分类号 |
C07D239/42;C07D417/06 |
主分类号 |
C07D239/42 |
| 代理机构 |
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代理人 |
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| 主权项 |
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