COATED MAGNETIC PARTICLE CONTAINING PREPARATION, PROCESS FOR PRODUCING THE SAME AND DIAGNOSTIC THERAPEUTIC SYSTEM

摘要

It is an object of the invention to provide a pharmaceutical preparation containing magnetic vesicular particles which enables selective delivery of agents to a tumor site (targeting capability), is applicable to a contrast medium material or drug transport carrier and is also usable in thermotherapy employing heat-generation, and diagnosis and treatment of cancer by combinations thereof, and further a manufacturing method thereof and a diagnostic therapeutic system by use thereof. There is disclosed a pharmaceutical preparation comprising magnetic vesicular particles, wherein the magnetic vesicular particles each include one or more magnetic microparticles within a lipid membrane, the magnetic microparticle having particulate gold attached to the surface of the magnetic microparticles and further having an organic compound bound to the particulate gold; and the vesicular particles meet the following requirement:
wherein R is an average particle size of the magnetic vesicular particles and r is an average particle size of the magnetic microparticles included in the magnetic vesicular particles.