| 摘要 |
A biosensor is provided to be employed for detecting specific protein, diagnosing cancer, measuring blood sugar, detecting harm virus and scanning environmental toxic materials and exhibit excellent electrical properties and high detection sensitivity. A biosensor comprises a solid substrate such as a silicon substrate and a glass substrate; at least one signal transducer which is arranged in a matrix and has nano wires to which electrodes are adhered; and at least one signal sensing part which is disposed in the vicinity of the nano wires. A receptor to be bound to a target material is adhered to the signal sensing part and is selected from the group consisting of enzyme-substrate, ligand, amino acid, peptide, protein, nucleic acid, lipid and carbohydrate, wherein the target material is at least one selected from the group consisting of a protein, a nucleic acid, oligosaccharide, an amino acid, a carbohydrate, a solute gas, a sulfur oxide gas, a nitrogen oxide gas, residual agricultural chemicals, a heavy metal and an environmental toxic material and the nano wire is at least one selected from the group consisting of a carbon nanotube, a silicon nano wire, a zinc oxide nano wire and a vanadium oxide nano wire. A method for manufacturing a biosensor comprising the steps of: (a) integrating nano wires on a surface of a solid substrate; (b) coating electrodes with a polymer after forming the electrodes at both ends of each of the nano wires; (c) adhering functional groups on the surface of the solid substrate between the nano wires; and (d) immobilizing a receptor through the functional groups which catalyzes or is bound to a target substance. A nano platform comprises at least one biosensor. |
