| 发明名称 |
INDOLE-TYPE DERIVATIVES AS INHIBITORS OF P38 KINASE |
| 摘要 |
The invention is directed to methods to inhibit p38-alpha kinase using compounds comprising a phenyl or thienyl coupled through a piperidine or piperazine nucleus to an indole residue wherein the indole residue mandatorily has a substituent on the ring nitrogen which is an amino or substituted amino group.
|
| 申请公布号 |
US2007232617(A1) |
申请公布日期 |
2007.10.04 |
| 申请号 |
US20070752255 |
申请日期 |
2007.05.22 |
| 申请人 |
SCIOS, INC. |
发明人 |
CHAKRAVARTY SARVAJIT;DUGAR SUNDEEP;LU QING;LUEDTKE GREGORY R.;MAVUNKEL BABU J.;PERUMATTAM JOHN J.;TESTER RICHARD W. |
| 分类号 |
A61K31/497;A61K31/445;C07D209/18;C07D209/42;C07D401/02;C07D401/06;C07D401/14;C07D403/02;C07D403/06;C07D409/12;C07D409/14 |
主分类号 |
A61K31/497 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
