CORE-SHELL NANOCAPSULES AND APPLICATIONS THEREOF

摘要

Core-shell nanocapsules containing a silica shell that is generally porous surrounds an oil core. A method to prepare the nanocapsules by preparing an oil-in-water-in-oil emulsion and carrying out a sol-gel synthesis of the silica from a tetraalkoxysilane in the water phase of the double micelle is described. The central oil core is prepared by the formation of a stabilized oil-in-water emulsion where an alkyltrialkoxysilane is included with the emulsion. The stabilized oil-in-water emulsion is then used as the aqueous phase to prepare the oil-in- water-in-oil emulsion. The nanocapsules can be used for drug detoxification applications.