发明名称 |
MODULATOR OF TNF/NGF SUPERFAMILY RECEPTORS AND SOLUBLE OLIGOMERIC TNF/NGF SUPERFAMILY RECEPTORS |
摘要 |
The present invention generally concerns novel proteins which bind to the intracellular domains of the p55 and p75 TNF-Rs and the FAS-R, which are capable of modulating the function of the p55 and p75 TNF-Rs and the FAS-R, and the DNA sequences which encode them. The present invention also concerns new soluble oligomeric TNF-Rs, oligomeric FAS-Rs and oligomeric receptors having a mixture of TNF-Rs and FAS-Rs. In addition, the present invention concerns methods of preparation and uses of all of the aforementioned.
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申请公布号 |
US2007232520(A1) |
申请公布日期 |
2007.10.04 |
申请号 |
US20060615609 |
申请日期 |
2006.12.22 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO., LTD. |
发明人 |
WALLACH DAVID;BOLDIN MARK;METT IGOR;VARFOLOMEEV EUGENE |
分类号 |
A61K48/00;A61K38/00;C07K14/00;C07K14/47;C07K14/525;C07K14/705;C07K14/715;C07K16/18;C12N5/06;C12N15/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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