发明名称 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER
摘要 Disclosed is a triprenyl phenol compound having a thrombolysis-enhancing activity. Also disclosed is a process for production of the triprenyl phenol compound. The triprenyl phenol compound is represented by the general formula (II) or (III): (II) (III) wherein R<SUP>1</SUP> represents an aromatic group having at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group as a substituent or a part of a substituent, or an aromatic group which has a secondary amino group and may have a nitrogen; R<SUP>4</SUP> in the general formula (III) represents an aroamtic amino acid residue represented by the general formula (III-1) below; X represents -CHY-(CH<SUB>3</SUB>)<SUB>2</SUB>Z; and Y and Z independently represent -H or =OH or together form a single bond: (III-1) wherein R<SUP>5</SUP> represents a hydroxyl group which may be absent; and n represents an integer of 0 or 1.
申请公布号 WO2007111203(A1) 申请公布日期 2007.10.04
申请号 WO2007JP55749 申请日期 2007.03.20
申请人 TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD.;HASUMI, KEIJI;KITANO, YOSHIKAZU;OHISHI, HIDEO;KOIDE, HARUKI;HASEGAWA, KEIKO;NARASAKI, RITSUKO 发明人 HASUMI, KEIJI;KITANO, YOSHIKAZU;OHISHI, HIDEO;KOIDE, HARUKI;HASEGAWA, KEIKO;NARASAKI, RITSUKO
分类号 C12P17/18;A61K31/407;A61P7/02;A61P9/00;C07D491/052 主分类号 C12P17/18
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