| 摘要 |
<p>[PROBLEMS] To provide a compound that exhibits excellent CCR4 or TARC and/or MDC function regulating activities and can be used in prevention and/or therapy for various inflammatory diseases, allergic diseases, autoimmune diseases, etc. [MEANS FOR SOLVING PROBLEMS] Acylaminopiperidine compounds of the formula (I) or pharmaceutically acceptable salts thereof. (I) In the formula, the characters have the following meaning. A: single bond or C<SUB>1</SUB>-C<SUB>6</SUB> alkylene. R<SUP>1</SUP>: optionally substituted phenyl, etc. R<SUP>2</SUP>: -H or C<SUB>1</SUB>-C<SUB>6</SUB> alkyl. R<SUP>3</SUP>: -H, C<SUB>1</SUB>-C<SUB>6</SUB> alkyl or C<SUB>3</SUB>-C<SUB>8</SUB> cycloalkyl. R<SUP>4</SUP>: optionally substituted pyrrolidin-2-yl, etc. D: benzene ring or pyrazole ring.</p> |
| 申请人 |
ASTELLAS PHARMA INC.;KONTANI, TORU;KAWANO, NORIYUKI;MASUDA, NAOYUKI;KATO, KOJI;NAGATA, HIROSHI;INAMI, HIROSHI;TERASAKA, TADASHI;YOKOYAMA, KAZUHIRO;MIYAZAKI, TAKAHIRO |
发明人 |
KONTANI, TORU;KAWANO, NORIYUKI;MASUDA, NAOYUKI;KATO, KOJI;NAGATA, HIROSHI;INAMI, HIROSHI;TERASAKA, TADASHI;YOKOYAMA, KAZUHIRO;MIYAZAKI, TAKAHIRO |
