发明名称 |
Patterned Cell Network Substrate Interface and Methods and Uses Thereof |
摘要 |
There is provided herein a method and apparatus suitable for use in studying cell membrane related activities. Activities of interest include patch-clamp related studies of networks of cells on a solid substrate. Cells are grown, preferably in a patterned manner, on a substrate having microholes therein. Seals between the cells and the microholes are formed. Each microhole is attached to a channel. In many cases only one hole will be attached to a single channel, allowing examination of effects of a stimulus at a number of different points in a network of one or more cell types. This may be interest, for example, to those wishing to study interactions between neurons or neuromuscular junctions.
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申请公布号 |
US2007231850(A1) |
申请公布日期 |
2007.10.04 |
申请号 |
US20060579729 |
申请日期 |
2006.11.06 |
申请人 |
GEOFFREY MEALING;PY CHRISTOPHE;MIKE DENHOFF;DOWLATSHAHI REZA;FAID KARIM;VOICU RALUCA;BANI MAHMUD |
发明人 |
GEOFFREY MEALING;PY CHRISTOPHE;MIKE DENHOFF;DOWLATSHAHI REZA;FAID KARIM;VOICU RALUCA;BANI MAHMUD |
分类号 |
C12M1/14;C12M1/34;C12Q1/02 |
主分类号 |
C12M1/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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