发明名称 |
Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof |
摘要 |
A method of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprises the steps of (a) preparing an antibody or antibody fragment; (b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome or with a cationic polymer to form a polyplex; and (c) mixing said cationic immunoliposome or said polyplex with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex.
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申请公布号 |
US2007231378(A1) |
申请公布日期 |
2007.10.04 |
申请号 |
US20070798296 |
申请日期 |
2007.05.11 |
申请人 |
GEORGETOWN UNIVERSITY |
发明人 |
CHANG ESTHER H.;PIROLLO KATHLEEN F. |
分类号 |
A61K9/127;A61K39/385;A61K39/395;A61K39/44;C07K16/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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