<p>Ester derivatives of the phenolic hydroxyl group of buprenorphine are described that can be used in the treatment of opiate dependency and/or moderate to severe pain. The esters have an enhanced bioavailability, an enhanced duration of action, and a reduced abuse potential.</p>
申请公布号
WO2007110636(A1)
申请公布日期
2007.10.04
申请号
WO2007GB01120
申请日期
2007.03.27
申请人
RECKITT BENCKISER HEALTHCARE (UK) LIMITED;CHAPLEO, CHRISTOPHER, BOURNE;LEWIS, JOHN, WILLIAM