发明名称 |
MOTION RESOLVED MOLECULAR SEQUENCING |
摘要 |
<p>Methods are provided for determining the sequence of a polynucleotide by tracking the motion of a nucleotide-selective, processive enzyme along a template, in a reaction mixture that alters the enzyme movement in a base specific manner. The movement trace of the enzyme is collected, and arranged in temporal order. The enzyme movement traces are correlated with the reaction conditions, and from these characteristic signals, the nucleotide sequence is derived.</p> |
申请公布号 |
WO2007111924(A2) |
申请公布日期 |
2007.10.04 |
申请号 |
WO2007US07085 |
申请日期 |
2007.03.21 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;BLOCK, STEVEN, M.;GREENLEAF, WILLIAM |
发明人 |
BLOCK, STEVEN, M.;GREENLEAF, WILLIAM |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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