Process for the preparation of enantiomerically enriched cyclic beta-aryl or heteroaryl carbocyclic acids

摘要

The present invention relates to a process for the preparation of cis substituted cyclic beta-aryl or heteroaryl carboxylic acid derivatives in high diastereo- and enantioselectivity by enantioselective hydrogenation in accordance with the following scheme wherein X, Ar, n, and m are defined herein and corresponding salts thereof.