发明名称 PHENOLIC HYDRAZONE MACROPHAGE MIGRATION INHIBITORY FACTOR INHIBITORS
摘要 Provided are various compounds of Formula (I): Also provided are pharmaceutical compositions comprising the above compounds. Additionally, methods of inhibiting macrophage migration inhibitory factor (MIF) activity in a mammal are provided, as are methods of treating or preventing inflammation in a mammal. Further provided are methods of treating a mammal having sepsis, septicemia, and/or endotoxic shock. Also provided are methods of treating a mammal having an autoimmune disease, and methods of treating a mammal having a tumor.
申请公布号 WO2007112015(A2) 申请公布日期 2007.10.04
申请号 WO2007US07277 申请日期 2007.03.23
申请人 THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH;AL-ABED, YOUSEF 发明人 AL-ABED, YOUSEF
分类号 A61K31/24 主分类号 A61K31/24
代理机构 代理人
主权项
地址