<p>Compositions and methods for preparing Factor IX, Factor IX-containing fusion proteins, and Factor IX-containing conjugates with processing of Factor IX propeptide by PC5, are provided. In one embodiment PC5 is used to process a precursor polypeptide for a Factor IX-Fc monomer-dimer hybrid.</p>
申请公布号
WO2007112005(A2)
申请公布日期
2007.10.04
申请号
WO2007US07252
申请日期
2007.03.23
申请人
SYNTONIX PHARMACEUTICALS, INC.;PETERS, ROBERT, T.;BITONTI, ALAN