HISTAMINE RELEASE INHIBITOR

摘要

Disclosed is a food or pharmaceutical composition for the treatment of a disease or condition associated with the release of histamine, which comprises a plant belonging to the genus Momordica. Preferred examples of the plant include balsam pear (Momordica charantia L.) and kakrol (Momordica dioica Roxb.) which grows in an area around Bangladesh. It is particularly preferable to use an aqueous extract of a pulp of the plant. The food or pharmaceutical composition is useful for a disease or condition associated with the release of histamine, such as atopic dermatitis, pollinosis, allergic rhinitis, allergic conjunctivitis, bronchial asthma, urticaria, collagen disease, hypersensitivity pneumonitis, anaphylaxis, food allergy, drug allergy, mite allergy, metal allergy and animal allergy.