发明名称 |
PHARMACEUTICAL METHODS, DOSING REGIMES AND DOSAGE FORMS FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
摘要 |
In general, the invention relates to a pharmaceutical dose having R-flurbiprofen as the active ingredient that upon oral administration of a single dose to a fasting subject provides a C<SUB>max </SUB>of about 30-95 mug per mL. When the dose is administered to an individual having mild-to-moderate Alzheimer's disease (or desiring protection against Alzheimer's disease) twice daily for at least 4 months according to the described guidelines, an improvement or lessening in decline of cognitive function as characterized by cognition tests is observed in the patient. The composition of the invention is formulated with one or more pharmaceutically acceptable excipients, salts or carriers. |
申请公布号 |
EP1651195(A4) |
申请公布日期 |
2007.10.03 |
申请号 |
EP20040821024 |
申请日期 |
2004.07.12 |
申请人 |
MYRIAD GENETICS, INC. |
发明人 |
HOBDEN, ADRIAN;ZAVITZ, KENTON;MATHER, GARY;HENDRIX, SUZANNE |
分类号 |
A61K9/48;A61K9/20;A61K9/28;A61K31/19;A61K31/192 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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