发明名称 |
CHIRAL HEPTYNE DERIVATIVES FOR THE PREPARATION OF EPOTHILONES AND PROCESSES FOR THEIR PREPARATION |
摘要 |
The invention relates to a new synthetic process for the production of key intermediates useful in the synthesis of epothilones or epothilone derivatives, to certain compounds used to produce these key intermediates and to a process to produce said compounds. <CHEM> <CHEM> <??>The intermediates used are represented by formulae II and III, wherein R is selected from H, alkyl and substituded alkyl and X1 is an oxygen protecting group. |
申请公布号 |
EP1758875(B1) |
申请公布日期 |
2007.10.03 |
申请号 |
EP20050740374 |
申请日期 |
2005.04.21 |
申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
PLATZEK, JOHANNES;PETROV, ORLIN;WILLUHN, MARC;GRASKE, KLAUS-DIETER;SKUBALLA, WERNER |
分类号 |
C07D309/12;C07D313/00;C07D409/12;C07D493/04 |
主分类号 |
C07D309/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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