| 发明名称 |
THERMALLY STABLE STORABLE CRYSTALLINE MODIFICATION OF N-METHYL-N-[(1S)-1-PHENYL-2-((3S)-3-HYDROXY-PYRROLIDIN-1-YL)ETHYL]-2,2-DIPHENYLACETAMIDE AND A PROCESS FOR ITS PREPARATION |
| 摘要 |
The invention relates to a novel heat-stable form of N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin- 1-yl)ethyl-2,2-diphenylacetamide and to a process for the preparation and isolation of this compound in this novel form, and to use for the production of medicaments which contain this compound and/or one of its physiologically acceptable salts.
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| 申请公布号 |
CA2184049(C) |
申请公布日期 |
2007.10.02 |
| 申请号 |
CA19962184049 |
申请日期 |
1996.08.23 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
STEIN, INGE;BARBER, ANDREW;NEUENFELD, STEFFEN;BESCHMANN, KLAUS;BEERES, HOLGER |
| 分类号 |
C07D207/12;A61K31/40;A61P1/00;A61P25/04;A61P29/00;C07B63/00 |
主分类号 |
C07D207/12 |
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