GROWTH RECEPTOR FACTOR BOUND PROTEIN 7 FUSION PROTEIN
摘要
A fusion protein of growth receptor factor bound protein 7(Grb7) is provided to increase cell penetration ability of the Grb7, so that atopic dermatitis is effectively treated, and skin cell and tissue are protected from atopic dermatitis. A cell-transducing fusion protein of growth receptor factor bound protein 7(Grb7) is produced by covalently binding PEP-1 protein-transducing domain to one terminal of the Grb7 and has the amino acid sequence of SEQ ID NO:7. An external skin composition for treating atopic dermatitis comprises the cell-transducing fusion protein of the Grb7 and pharmaceutically acceptable carriers.
申请公布号
KR20070096561(A)
申请公布日期
2007.10.02
申请号
KR20060027270
申请日期
2006.03.27
申请人
HALLYM UNIVERSITY
发明人
CHOI, SU YOUNG;PARK, JIN SEO;UM, WON SIK;KIM, DAE WON;CHOI, JIN HEE;KIM, TAE YOON;KWON, HYUNG JOO;LEE, SANG CHUL;BU, HA RYUNG