发明名称 Polynucleotides encoding a novel human G-protein coupled receptor splice variant, HGPRBMY29SV2
摘要 The present invention provides novel polynucleotides encoding HGPRBMY28 and HGPRBMY29 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding splice variants of HGPRBMY29 polypeptides, HGPRBMY29v1 and HGPRBMY29v2. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing these polypeptides. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing these polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY28, HGPRBMY29, HGPRBMY29v1, and HGPRBMY29v2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
申请公布号 US7276354(B2) 申请公布日期 2007.10.02
申请号 US20050071761 申请日期 2005.03.03
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 FEDER JOHN N.;RAMANATHAN CHANDRA S.;MINTIER GABRIEL A.;BOL DAVID
分类号 C12P21/06;A61K38/00;C07H21/04;C07K14/705;C12N1/20;C12N15/74 主分类号 C12P21/06
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