RECOMBINANT SEQUENCE-MODIFIED L.JOHNSONII BACTERIA WHICH PRODUCE ONLY L(+)-LACTATE

摘要

A RECOMBINANT STRAIN OF L. JOHNSONII WHICH HAS CAPACITIES OF SURVIVING PASSAGE THROUGH THE INTESTINE, ADHERING TO HUMAN INTESTINAL CELLS AND INCREASING PHAGOCYTOSIS OF MACROPHAGES AND WHICH HAS A GENE SEQUENCE CODE FOR D-LACTATE DEHYDROGENASE WHICH IS A MODIFIED L. JOHNSONII GENE SEQUENCE CODE AND WHICH PRODUCES ONLY L(+)-LACTATE.(FIG 4)