| 摘要 |
An intra-ruminal bolus that releases a therapeutically effective amount of at least one beneficial agent to a ruminant animal over a time period of less than approximately 21 days that includes: (a) at least one beneficial agent; (b) at least one densifier material; (c) at least one binding agent; (d) at least one releasing agent; and, characterised in that the ratio of binding agent to releasing agent ranges from approximately 1 part binding agent to between approximately 0.01 and approximately 2 parts releasing agent to achieve a sustained release rate over a time period of less than approximately 21 days.
|
