发明名称 |
MACROCYCLIC PEPTIDES AND METHODS FOR MAKING AND USING THEM |
摘要 |
<p>The invention provides novel macrocyclic peptides and methods for their preparation. The invention also provides pharmaceutical compositions and methods to treat, prevent or ameliorate a cell proliferative disease or conditions, e.g., a cancer, in a subject in need thereof, including but not limited to a colon cancer, such as MSS or MSI colon cancer, and pancreatic cancer. This invention provides for the synthesis and development of novel anticancer agents that are based on the core structure Sansalvamide A (San A).</p> |
申请公布号 |
WO2007109620(A2) |
申请公布日期 |
2007.09.27 |
申请号 |
WO2007US64317 |
申请日期 |
2007.03.19 |
申请人 |
SAN DIEGO STATE UNIVERSITY FOUNDATION;MCALPINE, SHELLI, R.;MCGUIRE, KATHLEEN |
发明人 |
MCALPINE, SHELLI, R.;MCGUIRE, KATHLEEN |
分类号 |
A61K38/12 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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