发明名称 |
METHODS TO MAINTAIN, IMPROVE AND RESTORE THE CARTILAGE PHENOTYPE OF CHONDROCYTES |
摘要 |
The present invention relates to regulatory cells, which are capable of restoring, maintaining or improving the stable cartilage phenotype of expanded and passaged chondrocytes. These regulatory cells are also capable of directing precursor and stem cells into the chondrogenic lineage. An enriched population of regulatory cells can be obtained by harvesting the non-adherent cells in the culture medium of a monolayer culture of PO chondrocytes. |
申请公布号 |
WO2007107330(A2) |
申请公布日期 |
2007.09.27 |
申请号 |
WO2007EP02452 |
申请日期 |
2007.03.20 |
申请人 |
TIGENIX N.V.;KNIPPER, ANDREAS;MUIR-MCLEOD, PAULA |
发明人 |
KNIPPER, ANDREAS;MUIR-MCLEOD, PAULA |
分类号 |
A61L27/38;C12N5/077 |
主分类号 |
A61L27/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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