| 摘要 |
The invention concerns benzamide compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R<SUP>1</SUP>, ring A, n, R<SUP>3</SUP>, and R<SUP>4</SUP> are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of EphB4, and/or EphA2 and/or Src kinases. |
| 申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;KETTLE, JASON, GRANT;READ, JON;LEACH, ANDREW;BARLAAM, BERNARD, CHRISTOPHE;DUCRAY, RICHARD;LAMBERT-VAN DER BREMPT, CHRISTINE, MARIE PAUL |
发明人 |
KETTLE, JASON, GRANT;READ, JON;LEACH, ANDREW;BARLAAM, BERNARD, CHRISTOPHE;DUCRAY, RICHARD;LAMBERT-VAN DER BREMPT, CHRISTINE, MARIE PAUL |
