<p>The invention concerns a novel moldable and/or flowable composition for application to a bone defect site to promote new bone growth at the site. The composition includes a therapeutic material and a carrier comprising means for achieving reverse phase characteristics. In one embodiment, the therapeutic material can be a resorbable alloplastic material and the carrier can be a poloxamer. In a specific embodiment, the resorbable alloplastic material is a biphasic material composed of hydroxyapatite and tricalcium phosphate (HA-TCP), and the carrier is poloxamer 407 (PLURONIC® F-127). The invention further includes methods for using the novel composition.</p>
申请公布号
WO2007107012(A1)
申请公布日期
2007.09.27
申请号
WO2007CA00476
申请日期
2007.03.23
申请人
CITAGENIX INC.;BOURGEOIS, NICOLAS;CLOKIE, CAMERON, M.L.;TRITTHARDT, UWE;MCMILLAN, MICHAEL
发明人
BOURGEOIS, NICOLAS;CLOKIE, CAMERON, M.L.;TRITTHARDT, UWE;MCMILLAN, MICHAEL