发明名称 (5-CARBOXAMIDO OR 5-FLUORO)-(2',3'-UNSATURATED OR 3'-MODIFIED)-PYRIMIDINE NUCLEOSIDE
摘要 PROBLEM TO BE SOLVED: To provide a method and composition for the treatment of HIV and HBV infection of human and other host animals. SOLUTION: The composition is composed of a pharmaceutically acceptable carrier containing a (5-carboxamido or 5-fluoro)-2',3'-dideoxy-2',3'-didehydropyrimidine nucleoside or a (5-carboxamido or 5-fluoro)-3'-modified-pyrimidine nucleoside, a mixture of the nucleosides, a pharmaceutically acceptable derivative including an N-1 or N-4 alkylated or acylated derivative of the nucleoside, etc., or a pharmaceutically acceptable salt of the nucleoside. COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007246540(A) 申请公布日期 2007.09.27
申请号 JP20070132413 申请日期 2007.05.18
申请人 EMORY UNIV 发明人 SCHINAZI RAYMOND F;LIOTTA DENNIS C
分类号 A61K31/52;C07D239/34;A61K9/20;A61K31/505;A61K31/506;A61K31/513;A61K31/522;A61K31/6615;A61K31/675;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K31/7072;A61K38/21;A61K45/06;A61P31/12;A61P31/18;A61P31/20;A61P37/04;C07D239/38;C07D405/04;C07H19/06 主分类号 A61K31/52
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