IMPROVEMENTS IN TREATMENT OF DRY POWDER FORMULATIONS

摘要

The present invention relates to the treatment of dry powder formulations, doses of which are measured out and placed into receptacles such as blisters or capsules, to be dispensed by a dry powder inhaler device (DPI). In particular, the present invention relates to methods of agitating a dose of a dry powder formulation to ensure that any compacted powder is broken up. It is easier to extract a loose powder from a receptacle than it is to extract powder which is compacted and so ensuring that the powder in a receptacle is not compacted can, in turn, lead to improvements in the administration of the powder formulation to the lung of the patient.