发明名称 Substituted dibenzo-azepine and benzo-diazepine derivatives useful as gamma-secretase inhibitors
摘要 The present invention provides compounds of the general formula wherein R<SUP>4 </SUP>is one of the following groups and R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, and R<SUP>9 </SUP>are as defined in the specification and pharmaceutically acceptable salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. The compounds are useful for the treatment of Alzheimer's disease.
申请公布号 ZA200602802(B) 申请公布日期 2007.09.26
申请号 ZA20060002802 申请日期 2006.04.05
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 FLOHR, ALEXANDER;JAKOB-ROETNE, ROLAND;PETERS, JENS-UWE;GALLEY, GUIDO;KITAS, ERIC ARGIRIOS;WOSTL, WOLFGANG
分类号 A61K;A61P;C07D;C07D223/16;C07D223/18;C07D243/12;C07D243/24;C07D409/12 主分类号 A61K
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