| 发明名称 |
Macrocyclic inhibitors of HCV NS3 serine protease |
| 摘要 |
The present invention discloses novel compounds which have HCV protease inhibitory activity as well as pharmaceutical compositions comprising such compounds and methods of using them to treat disorders associated with the HCV protease. The novel compounds typically include a 15-20 member macrocycle and have the general structure of structural Formula 1: wherein Z', L', M', R1, X and D are defined herein. |
| 申请公布号 |
ZA200602447(B) |
申请公布日期 |
2007.09.26 |
| 申请号 |
ZA20060002447 |
申请日期 |
2006.03.24 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
VENTKATRAMAN, SRIKANTH;WU, WANLI;MCKITTRICK, BRIAN;VELASQUEZ, FRANCISCO;NJOROGE, F. GEORGE;GIRIJAVALLABHAN, VIYYOOR M.;SU, JING;PINTO, PATRICK A. |
| 分类号 |
A61K;A61K31/33;A61K38/00;A61K38/12;A61K38/21;C07D;C07D245/04;C07D401/12;C07D403/12;C07D409/12;C07D487/04;C07D513/04;C07K;C07K5/02;C07K5/08 |
主分类号 |
A61K |
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