| 发明名称 |
VERFAHREN ZUR HERSTELLUNG EINES PIPERAZINDERIVATES |
| 摘要 |
A process for preparing a piperazine derivative represented by the formula (V): <CHEM> comprising reacting 1-methyl-3-phenylpiperazine with 2-chloro-3-cyanopyridine in an aprotic polar organic solvent in the presence of a base and an alkali metal halide. The piperazine derivative and its oxalate are compounds useful as preparation intermediates of mirtazapine. |
| 申请公布号 |
AT370736(T) |
申请公布日期 |
2007.09.15 |
| 申请号 |
AT20000962874T |
申请日期 |
2000.09.27 |
| 申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
MAEDA, CHIHARU;IISHI, EIICHI;WANG, WEIQI;IMAMIYA, YOSHIYUKI |
| 分类号 |
A61K31/517;C07C209/74;C07C211/29;C07C213/04;C07C215/30;C07D213/85;C07D241/04;C07D401/04 |
主分类号 |
A61K31/517 |
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