METHODE ZUR REDUZIERUNG DER MESSABWEICHUNG VON AMPEROMETRISCHEN BIOSENSOREN

摘要

The present invention provides a method for determining the concentration of an analyte in a test sample, comprising the following steps: (a) assembling an amperometric biosensor, which comprises at least an electrode system and an electric mediator for redox, and applying a predetermined potential to the electrode system; (b) applying a test sample to the biosensor and immediately gradually lowering the predetermined potential to a value unable to drive the electrochemical redox of the electric mediator; (c) after a sufficient reaction time, applying a second potential to the electrode system of the biosensor to drive the electrochemical redox of the electric mediator; and (d) measuring the electrochemical current of the electrode system and determining the concentration of the analyte.