发明名称 LIPIDISIERUNG HYDROPHILER MOLEKÜLE
摘要 The invention provides uses of lipid-containing moieties in the manufacture of compounds for delivery of sulfhydryl group-containing compounds into mammalian cells. The sulfhydryl group-containing moieties are suitably peptides, proteins or oligonucleotides which contain or have been modified to contain sulfhdryl group. The lipid-containing moiety is conjugated to the sulfhydryl group-containing moiety via a disulphide linkage. Preferred lipid-containing moieties are described. <IMAGE>
申请公布号 AT371643(T) 申请公布日期 2007.09.15
申请号 AT20030006780T 申请日期 1996.01.25
申请人 UNIVERSITY OF SOUTHERN CALIFORNIA 发明人 SHEN, WEI-CHIANG;EKRAMI, HOSSEIN M.
分类号 C07C321/28;C12N9/02;A61K31/70;A61K38/00;A61K38/17;A61K47/48;C07C323/58;C07D213/70;C07D213/71;C07H21/00;C07K1/113;C07K14/47;C12N9/08 主分类号 C07C321/28
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