发明名称 GROWTH FACTOR THERAPY MOBILIZATION OF STEM CELLS INTO THE PERIPHERAL BLOOD
摘要 Stem cells are mobilized into the peripheral blood by a method comprising the steps of: (i) administering to an individual at least one of the following: FGFl and FGF2, and also at least one of the following: VEGF, VEGFA and VEGF 165; (ii) isolating the peripheral blood stem cells (PBSC) by apheresis; and (iii) injecting the PBSC into a patient suffering from chronic heart disease. Alternatively, gene therapy is used for the induction of the stem cells into the peripheral blood, wherein the gene therapy formulation comprises AD5FGF-4 or VEGF 165 plasmid DNA. Additionally, the progress of the treatment of the chronic heart disease is monitored by using an echocardiogram unit.
申请公布号 WO2006074182(A3) 申请公布日期 2007.09.13
申请号 WO2006US00115 申请日期 2006.01.04
申请人 FRANCO, WAYME 发明人
分类号 A61K38/00;A61K35/12;A61K35/14;A61K38/18;A61K45/00;A61K48/00;C12N5/0789 主分类号 A61K38/00
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