| 摘要 |
PROBLEM TO BE SOLVED: To provide a novel method for preparing N, N-dimethylcarbamoylmethyl 4-hydroxyphenylacetate useful as a production intermediate for a medicine. SOLUTION: The method for preparing N, N-dimethylcarbamoylmethyl 4-hydroxyphenylacetate is characterized by causing 4-hydroxyphenylacetate and 2-bromo-N, N-dimethylacetamide or 2-chloro-N, N-dimethylacetamide to react with each other in water or in a mixed solvent of water and an organic solvent compatible with water in the presence of an alkali. The method according to the present invention allows the reaction to proceed at a high reaction rate and makes an aftertreatment subsequent to the reaction easy and simple. COPYRIGHT: (C)2007,JPO&INPIT
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