| 摘要 |
<p>The present invention if directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and processes for preparing such compounds. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.</p> |
| 申请人 |
AMGEN INC.;MEMORY PHARMACEUTICALS CORPORATION;ARRINGTON, MARK, P.;HOPPER, ALLEN, T.;CONTICELLO, RICHARD, D.;NGUYEN, TRUC, M.;HESS, HANS-JURGEN;GAUSS, CARLA;HITCHCOCK, STEPHEN, A. |
发明人 |
ARRINGTON, MARK, P.;HOPPER, ALLEN, T.;CONTICELLO, RICHARD, D.;NGUYEN, TRUC, M.;HESS, HANS-JURGEN;GAUSS, CARLA;HITCHCOCK, STEPHEN, A. |
